Combining expertise in HEOR & Market Access.
HEOR: Health Economics and Outcomes Research
Connor Buffel
CEO
Connor holds a Master’s of Biomedical Technology. His focus on the crossroads of science and business is ideally suited to deliver client value in market access. Connor has a strong interest in highly specialized technologies, such as gene therapy, where innovative modeling approaches and value communication strategies are critical for success.
Tinne Braspenning
COO & CFO / HEOR & Market Access Consultant
Tinne is an Economist by education with a broad interest in data analyses, value communication, and project management. As COO/CFO, she is overlooking day-to-day administrative and operational functions and managing financial actions within ISMS . Besides, Tinne has a hands-on experience in HEOR & Market Access projects bringing them to a next level while safeguarding quality, budget, and timelines.
Geert Vander Stichele
CSO
His passion for healthcare and modeling sent him to KU Leuven where he combined a Pharmaceutical Science degree with a Master in Econometrics. The drive for creativity and independence resulted in the creation of his own company (ISMS) where he put together a team that developed communication campaigns for doctors and patients for pharmaceutical companies, in addition to building economic models.
David (Xin) Zhao
Modeling Analyst, Genetic Epidemiology
David holds a Ph.D. in Food Microbiology with a strong foundation in leveraging machine learning for medical applications. His expertise lies at the intersection of cutting-edge AI-technology, bioinformatics and healthcare innovation, ensuring impactful client solutions in digital health. David is passionate about bridging microbiology and epidemiology with computational biology and advancing data and AI-driven methodologies to address complex challenges in healthcare and biotech.
Simon Wilms
HEOR & Market Access Analyst
Simon holds a Master’s degree in Drug Development and brings cross-functional expertise spanning health economic modelling, value communication and market access strategy. At ISMS, he contributes to the development of materials and services across the HEOR spectrum. This ranges from HTA submissions and cost-effectiveness models to evidence synthesis and value-based pricing analyses. He is driven by turning data into strategic insights to support reimbursement decisions and improve patient access to innovative therapies.
Michelle Luypaert
Science & Value Communication Consultant
As Master in Clinical Biomedical Sciences with a focus on the detail-oriented, problem solving and creative side, Michelle has a broad background and expertise. She doesn’t only contribute to conceptual and scientific aspects of the models and tools we develop at ISMS, but also to clear, targeted communication and design. Creating the best product to improve health and quality of life of patients as a team gives her great fulfillment.
Charles Vertongen
HEOR & Market Access Analyst
Charles holds a Master degree in Cellular and Genetic Engineering. At ISMS, he supports the development of high-quality HEOR and Market Access projects by combining analytical rigor with clear communication and dedication to innovation. With a keen eye for detail and a results-oriented mindset, Charles contributes to delivering impactful insights that support decision-making and strategic value demonstration.
Stéphanie Sterckx
Management Assistant
Stéphanie brings broad experience in administrative coordination across sectors. Her energetic personality, combined with a structured and detail-oriented approach, ensures smooth and efficient team operations. She thrives as a freelancer in dynamic environments where adaptability and clear communication are essential.
Abdullah Zubair
Modeling Analyst, Genetic Epidemiology
Abdullah holds a Bachelor of Health Sciences in Bioinformatics from the University of Calgary. He combines expertise in bioinformatics, machine learning, and data science to build scalable models that advance data-driven healthcare innovation. His experience includes enhancing predictive modeling for disease risk, data analysis, and data visualization. He is passionate about leveraging AI to turn data into actionable insights and drive transformative healthcare solutions.
HEOR: Health Economics and Outcomes Research; HTA: health technology assessment